Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

Elizabeth A. Grimm, A Mazumder, H Z Zhang et al. · The Journal of Experimental Medicine · 1982 · 2.2K citations · Full text

Life Sciences, Immunology, Oncology +15

Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer

Jeffrey S. Miller, Yvette Soignier, Angela Panoskaltsis‐Mortari et al. · Blood · 2005 · 1.9K citations · Full text

Life Sciences, Immunology, Oncology +13

NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

Massimo Vitale, Cristina Bottino, Simona Sivori et al. · The Journal of Experimental Medicine · 1998 · 722 citations · Full text

Life Sciences, Cell Biology, Immunology +12

A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency.

Peihua Lu, Robert S. Negrin · The Journal of Immunology · 1994 · 433 citations

Life Sciences, Cell Biology, Immunology +15

Lymphokine-activated killer cells: A new approach to immunotherapy of cancer

Steven A. Rosenberg · JNCI Journal of the National Cancer Institute · 1985 · 308 citations · Full text

Life Sciences, Immunology, Oncology +14