Concepedia

Local RNA Target Structure Influences siRNA Efficacy: Systematic Analysis of Intentionally Designed Binding Regions

Steffen Schubert, Arnold Grünweller, Volker A. Erdmann, Jens Kurreck

Journal of Molecular Biology · 2005 · 247 citations · 37 references

DOI

Concepts

References

37

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

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Mfold web server for nucleic acid folding and hybridization prediction

Michael Zuker · Nucleic Acids Research · 2003 · 13.6K citations · Full text

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

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Asymmetry in the Assembly of the RNAi Enzyme Complex

Dianne S. Schwarz, György Hutvágner, Tingting Du et al. · Cell · 2003 · 2.8K citations · Full text

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Functional siRNAs and miRNAs Exhibit Strand Bias

Anastasia Khvorova, Angela Reynolds, Sumedha D. Jayasena · Cell · 2003 · 2.6K citations · Full text

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