Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A

Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4

Roel A. Ophoff, Gisela M. Terwindt, Monique N. Vergouwe et al. · Cell · 1996 · 2.3K citations · Full text

Life Sciences, Neurology, Neuroscience +16

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the α1A-voltage-dependent calcium channel

Olga Zhuchenko, Jennifer M. Bailey, Penelope E. Bonnen et al. · Nature Genetics · 1997 · 1.6K citations

Life Sciences, Genetics, Neurology +16

A Cacna1a Knockin Migraine Mouse Model with Increased Susceptibility to Cortical Spreading Depression

Arn M. J. M. van den Maagdenberg, Daniela Pietrobon, Tommaso Pizzorusso et al. · Neuron · 2004 · 690 citations · Full text

Life Sciences, Neurology, Neuroscience +8

The Clinical Spectrum of Familial Hemiplegic Migraine Associated with Mutations in a Neuronal Calcium Channel

Anne Ducros, Christian Denier, Anne Joutel et al. · New England Journal of Medicine · 2001 · 561 citations · Full text

Life Sciences, Genetics, Neurology +16

Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia

Joy T. Walter, Karina Alviña, Mary D. Womack et al. · Nature Neuroscience · 2006 · 434 citations

Life Sciences, Neurobiology, Neuroscience +14