Passive Smoking Impairs Histone Deacetylase-2 in Children With Severe Asthma

Asthma Control Test: Reliability, validity, and responsiveness in patients not previously followed by asthma specialists

Michael Schatz, Christine A. Sorkness, James T. Li et al. · Journal of Allergy and Clinical Immunology · 2006 · 1.2K citations

Asthma, Reliability, Pulmonary Care +6

Decreased Histone Deacetylase Activity in Chronic Obstructive Pulmonary Disease

Kazuhiro Ito, Misako Ito, W. Mark Elliott et al. · New England Journal of Medicine · 2005 · 955 citations · Full text

Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression

Kazuhiro Ito, Satoshi Yamamura, Sarah Essilfie-Quaye et al. · The Journal of Experimental Medicine · 2005 · 613 citations · Full text

Theophylline Restores Histone Deacetylase Activity and Steroid Responses in COPD Macrophages

Borja G. Cosío, Loukia Tsaprouni, Kazuhiro Ito et al. · The Journal of Experimental Medicine · 2004 · 478 citations · Full text

Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages

Kazuhiro Ito, Shuang Fang Lim, Gaetano Caramori et al. · The FASEB Journal · 2001 · 453 citations

Deacetylase 2, Inflammatory Lung Disease, Lung Inflammation +18