Reticulon family members modulate BACE1 activity and amyloid-β peptide generation

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Purification and cloning of amyloid precursor protein β-secretase from human brain

Sukanto Sinha, John P. Anderson, Robin Barbour et al. · Nature · 1999 · 1.6K citations

Life Sciences, Biochemistry, Neuroscience +14

Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

Maio S. Chen, Andrea B. Huber, Marjan E. van der Haar et al. · Nature · 2000 · 1.4K citations

Medicine, Neurobiology, Neuroscience +12

Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

Riqiang Yan, Michael J. Bienkowski, Mary E. Shuck et al. · Nature · 1999 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +14

Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein

Tadzia GrandPré, Fumio Nakamura, Timothy Vartanian et al. · Nature · 2000 · 1.1K citations

Medicine, Molecular Biology, Neuroscience +12