Synthetic DNA-compacting peptides derived from human sequence enhance cationic lipid-mediated gene transfer in vitro and in vivo

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

Gary J. Nabel, E G Nabel, Zhiyong Yang et al. · Proceedings of the National Academy of Sciences · 1993 · 890 citations

Medicine, Biotechnology, Oncology +17

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer

Hassan Farhood, Natalya V. Serbina, Leaf Huang · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1995 · 791 citations

Pharmacy, Biochemistry, Molecular Biology +13

Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.

Ernst Wagner, Christian Plank, Kurt Zatloukal et al. · Proceedings of the National Academy of Sciences · 1992 · 656 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Transferrin-polycation conjugates as carriers for DNA uptake into cells.

Ernst Wagner, Martin Zenke, Matthew Cotten et al. · Proceedings of the National Academy of Sciences · 1990 · 656 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15