Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

Miguel A. Ondetti, Bernard Rubin, David W. Cushman · Science · 1977 · 1.9K citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Role of xanthine oxidase inhibitor as free radical scavenger: A novel mechanism of action of allopurinol and oxypurinol in myocardial salvage

Dipak K. Das, Richard M. Engelman, Ronald Clement et al. · Biochemical and Biophysical Research Communications · 1987 · 205 citations

Medicine, Cardiology, Pharmacology +10

Reduction of reperfusion arrhythmias in the ischemic isolated rat heart by angiotensin converting enzyme inhibitors: a comparison of captopril, enalapril, and HOE 498.

Wiek H. van Gilst, de Pieter Graeff, H. Wesseling et al. · PubMed · 1986 · 202 citations

Medicine, Cardiology, Pharmacology +16

CAPTOPRIL: A NEW TREATMENT FOR RHEUMATOID ARTHRITIS?

M F Martin, Frank McKenna, H. A. Bird et al. · The Lancet · 1984 · 161 citations

Medicine, Internal Medicine, Pharmacotherapy +8

Pathophysiology of superoxide radical as potential mediator of reperfusion injury in pig heart

Dipak K. Das, Richard M. Engelman, J. A. Rousou et al. · Basic Research in Cardiology · 1986 · 117 citations

Life Sciences, Cardiology, Physiology +15