Rapid desensitization determines the pharmacology of glutamate neurotoxicity

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

Blockade of <i>N</i> -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

R. P. Simon, J. H. Swan, T. Griffiths et al. · Science · 1984 · 1.7K citations

Life Sciences, Neuroscience, Pharmacology +17

Calcium Dependence of Toxic Cell Death: A Final Common Pathway

Francis A.X. Schanne, Agnes B. Kane, Ellora E. Young et al. · Science · 1979 · 1.5K citations

Veterinary Medicine, Cell Biology, Toxicology +16

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

Malcolm J. Sheardown, Elsebet Ø. Nielsen, Anker Jón Hansen et al. · Science · 1990 · 1.1K citations

Medicine, Neuroscience, Pharmacology +16