Concepedia

Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity

Megan K. Dennis, Angela S. Field, Ritwik Burai, Chinnasamy Ramesh, Whitney K. Petrie, Cristian Bologa, Tudor I. Oprea, Yuri Yamaguchi, Shinichi Hayashi, Larry A. Sklar,

The Journal of Steroid Biochemistry and Molecular Biology · 2011 · 306 citations · 27 references

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27

Molecular basis of agonism and antagonism in the oestrogen receptor

A.M. Brzozowski, A.C.W. Pike, Zbigniew Dauter et al. · Nature · 1997 · 3.3K citations

, , +14

A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling

Chetana M. Revankar, Daniel F. Cimino, Larry A. Sklar et al. · Science · 2005 · 2.3K citations

, , +10

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

Edward J. Filardo, Jeffrey A. Quinn, Kirby I. Bland et al. · Molecular Endocrinology · 2000 · 1.3K citations · Full text

, , +17

Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors

Stavroula Kousteni, Teresita Bellido, Lilian I. Plotkin et al. · Cell · 2001 · 1.1K citations · Full text

, , +14

Virtual and biomolecular screening converge on a selective agonist for GPR30

Cristian Bologa, Chetana M. Revankar, Susan Young et al. · Nature Chemical Biology · 2006 · 814 citations · Full text

, , +12