PLoS ONE · 2014 · 134 citations · 43 references
MedicineGeriatric MedicineHealth SciencesGeriatric AssessmentGerontologyPhysical ActivityAge DifferencesFunctional Assessment In Older AdultsGait AnalysisGait AssessmentGait EvaluationPhysical Performance AssessmentAge-related Gait ChangesAge-related Motor DifferencesGait Speed MeasurementHand Muscle Strength AssessmentLongitudinal Cohort StudiesSex-specific Reference ValuesStep LengthStep Length Analysis
OBJECTIVES: To determine age- and sex-specific reference values for six physical performance measures, i.e. hand-grip strength, one-legged stance, and gait speed and step length at both usual and maximum paces, and to investigate age and sex differences in these measures among community-dwelling older Japanese adults. METHODS: We conducted a pooled analysis of data from six cohort studies collected between 2002 and 2011 as part of the Tokyo Metropolitan Institute of Gerontology-Longitudinal Interdisciplinary Study on Aging. The pooled analysis included cross-sectional data from 4683 nondisabled, community-dwelling adults aged 65 years or older (2168 men, 2515 women; mean age: 74.0 years in men and 73.9 years in women). RESULTS: Unweighted simple mean (standard deviation) hand-grip strength, one-legged stance, usual gait speed, usual gait step length, maximum gait speed, and maximum gait step length were 31.7 (6.7) kg, 39.3 (23.0) s, 1.29 (0.25) m/s, 67.7 (10.0) cm, 1.94 (0.38) m/s, and 82.3 (11.6) cm, respectively, in men and 20.4 (5.0) kg, 36.8 (23.4) s, 1.25 (0.27) m/s, 60.8 (10.0) cm, 1.73 (0.36) m/s, and 69.7 (10.8) cm, respectively, in women. All physical performance measures showed significant decreasing trends with advancing age in both sexes (all P<0.001 for trend). We also constructed age- and sex-specific appraisal standards according to quintiles. With increasing age, the sex difference in hand-grip strength decreased significantly (P<0.001 for age and sex interaction). In contrast, sex differences significantly increased in all other measures (all P<0.05 for interactions) except step length at maximum pace. CONCLUSION: Our pooled analysis yielded inclusive age- and sex-specific reference values and appraisal standards for major physical performance measures in nondisabled, community-dwelling, older Japanese adults. The characteristics of age-related decline in physical performance measures differed between sexes.
43
Multiple regression: testing and interpreting interactions
Choice Reviews Online · 1992 · 37.2K citations
Quantifying heterogeneity in a meta‐analysis
Julian P. T. Higgins, Simon G. Thompson · Statistics in Medicine · 2002 · 36.7K citations
Frailty in Older Adults: Evidence for a Phenotype
Linda P. Fried, Catherine M. Tangen, Jeremy Walston et al. · The Journals of Gerontology Series A · 2001 · 24.5K citations · Full text
Gait Speed and Survival in Older Adults
Stephanie A. Studenski · JAMA · 2011 · 4.4K citations