Production and Proteomic Characterization of Pharmaceutical-Grade <i>Dermatophagoides pteronyssinus </i>and <i>Dermatophagoides farinae </i>Extracts for Allergy Vaccines

Abstract

We developed a well-defined medium allowing to grow various HDM species at an industrial scale in a highly reproducible manner. Extracts from mites produced under such pharmaceutical conditions contain all the relevant allergens for desensitization purposes and in vivo diagnosis.