Expanding expression of the 5-lipoxygenase/leukotriene B4 pathway in atherosclerotic lesions of diabetic patients promotes plaque instability

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J. Frederick Woessner · The FASEB Journal · 1991 · 3.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

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Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology.

Allard C. van der Wal, A E Becker, Chris M. van der Loos et al. · Circulation · 1994 · 1.9K citations · Full text

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North American Symptomatic Carotid Endarterectomy Trial. Methods, patient characteristics, and progress.

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Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture.

Prediman K. Shah, Edmund Falk, Juan J. Badimón et al. · PubMed · 1995 · 722 citations

Medicine, Cardiology, Pathology +17