Prediman K. Shah

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

Kathrin S. Michelsen, Michelle Wong, Prediman K. Shah et al. · Proceedings of the National Academy of Sciences · 2004 · 1K citations · Full text

Life Sciences, Immunology, Pathobiology +17

Pravastatin Treatment Increases Collagen Content and Decreases Lipid Content, Inflammation, Metalloproteinases, and Cell Death in Human Carotid Plaques

Milita Crisby, Gunilla Nordin-Fredriksson, Prediman K. Shah et al. · Circulation · 2001 · 999 citations

Medicine, Pharmacotherapy, Surgery +17

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

Marina Cuchel, Emma A. Meagher, Hendrik du Toit Theron et al. · The Lancet · 2012 · 740 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +12

Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture.

Prediman K. Shah, Edmund Falk, Juan J. Badimón et al. · PubMed · 1995 · 722 citations

Medicine, Cardiology, Pathology +17

Toll-Like Receptor-4 Is Expressed by Macrophages in Murine and Human Lipid-Rich Atherosclerotic Plaques and Upregulated by Oxidized LDL

Xiao-Ou Helen Xu, Prediman K. Shah, Emmanuelle Faure et al. · Circulation · 2001 · 667 citations

Life Sciences, Immunology, Pathobiology +17