Cti6, a PHD Domain Protein, Bridges the Cyc8-Tup1 Corepressor and the SAGA Coactivator to Overcome Repression at GAL1

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

Patrick A. Grant, Laura J. Duggan, Jacques Côté et al. · Genes & Development · 1997 · 1.1K citations · Full text

Genetics, Molecular Biology, Molecular Genetics +21

Ssn6-Tup1 is a general repressor of transcription in yeast

Cynthia A. Keleher, Michael J. Redd, Janet Schultz et al. · Cell · 1992 · 672 citations

Transcriptional Regulation, General Repressor, Natural Sciences +4

Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters

David Kadosh, Kevin Struhl · Cell · 1997 · 544 citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +13

Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2α subunit of NuRD

D. Schultz, Josh R. Friedman, Frank J. Rauscher · Genes & Development · 2001 · 518 citations · Full text

The DNA Replication and Damage Checkpoint Pathways Induce Transcription by Inhibition of the Crt1 Repressor

Mingxia Huang, Zheng Zhou, Stephen J. Elledge · Cell · 1998 · 514 citations · Full text

Chromatin, Genome Instability, Transcriptional Regulation +10