Laura J. Duggan

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

Patrick A. Grant, Laura J. Duggan, Jacques Côté et al. · Genes & Development · 1997 · 1.1K citations · Full text

Genetics, Molecular Biology, Molecular Genetics +21

Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8

Karl W. Henry, Anastasia Wyce, Wan-Sheng Lo et al. · Genes & Development · 2003 · 697 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +18

Phosphorylation of Serine 10 in Histone H3 Is Functionally Linked In Vitro and In Vivo to Gcn5-Mediated Acetylation at Lysine 14

Wan-Sheng Lo, Raymond C. Trievel, Jeannie R. Rojas et al. · Molecular Cell · 2000 · 567 citations · Full text

Chromatin, Signal Transduction, Chromatin Remodeling +13

Snf1--a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription

Wan‐Sheng Lo, Laura J. Duggan, N. C. Tolga et al. · Science · 2001 · 365 citations

Molecular Regulation, Genetics, Histone Acetyltransferase Gcn5 +18

Functional Organization of the Yeast SAGA Complex: Distinct Components Involved in Structural Integrity, Nucleosome Acetylation, and TATA-Binding Protein Interaction

David E. Sterner, Patrick A. Grant, Shannon M. Roberts et al. · Molecular and Cellular Biology · 1999 · 360 citations