Concepedia

Role of LPS/CD14/TLR4-mediated inflammation in necrotizing enterocolitis: Pathogenesis and therapeutic implications

Kwong Leung Chan, Kwong F. Wong, John M. Luk

World Journal of Gastroenterology · 2009 · 65 citations · 16 references

DOIFull text

Open access

Abstract

LPS and distension are required to produce the histological and inflammatory features of NEC. A potential treatment option is blocking LPS activation and leukocyte infiltration.

References

16

A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair

Cynthia L. Leaphart, Jaime A. Cavallo, Steven C. Gribar et al. · The Journal of Immunology · 2007 · 470 citations · Full text

Prolonging Small Feeding Volumes Early in Life Decreases the Incidence of Necrotizing Enterocolitis in Very Low Birth Weight Infants

Carol Lynn Berseth, Jennifer A. Bisquera, Virna U. Paje · PEDIATRICS · 2003 · 329 citations

Pathology of neonatal necrotizing enterocolitis: A ten-year experience

William A. Ballance, Beverly Barrett Dahms, Nancy Shenker et al. · The Journal of Pediatrics · 1990 · 308 citations

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Bifidobacterial supplementation reduces the incidence of necrotizing enterocolitis in a neonatal rat model

Michael S. Caplan, Robin Miller–Catchpole, Susan M. Kaup et al. · Gastroenterology · 1999 · 272 citations · Full text

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The Incidence of Necrotizing Enterocolitis After Introducing Standardized Feeding Schedules for Infants Between 1250 and 2500 Grams and Less Than 35 Weeks of Gestation

Michael Kamitsuka, Mary Horton, Michelle A. Williams · PEDIATRICS · 2000 · 140 citations