Histological Evidence of Oxidative Stress and Premature Senescence in Preterm Premature Rupture of the Human Fetal Membranes Recapitulated in Vitro

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5K citations · Full text

Developmental Biology, Oncogenic Agent, Cellular Senescence +6

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

Jean‐Philippe Coppé · 2008 · 4K citations · Full text

Oncogenic Ras, Health Sciences, Medicine +13

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

Françis Rodier, Jean‐Philippe Coppé, Christopher K. Patil et al. · Nature Cell Biology · 2009 · 2.1K citations · Full text

Inflammation, Dna Damage, Aging +8

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

Frédérique Zindy, Christine M. Eischen, David H. Randle et al. · Genes & Development · 1998 · 1.2K citations · Full text

p38MAPK is a novel DNA damage response‐independent regulator of the senescence‐associated secretory phenotype

Adam Freund, Christopher K. Patil, Judith Campisi · The EMBO Journal · 2011 · 980 citations · Full text