Insertion/Deletion Polymorphism of the Angiotensin I-Converting Enzyme Gene Is Associated With Coronary Artery Plaque Calcification As Assessed by Intravascular Ultrasound

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

Brigitte Rigat, C. Hübert, F Alhenc‐Gelas et al. · Journal of Clinical Investigation · 1990 · 3.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

François Cambien, Odette Poirier, Laure Lecerf et al. · Nature · 1992 · 1.9K citations

Medicine, Genetics, Molecular Genetics +14

Coronary Artery Calcification: Pathophysiology, Epidemiology, Imaging Methods, and Clinical Implications

Lewis Wexler, Bruce H. Brundage, John R. Crouse et al. · Circulation · 1996 · 1.1K citations

Medicine, Cardiology, Radiology +16

A Prospective Evaluation of an Angiotensin-Converting–Enzyme Gene Polymorphism and the Risk of Ischemic Heart Disease

Klaus Lindpaintner, Marc A. Pfeffer, Reinhold Kreutz et al. · New England Journal of Medicine · 1995 · 910 citations · Full text

Life Sciences, Cardiology, Genetics +11

Angiotensin-Converting Enzyme in the Human Heart

A.H. Jan Danser, Maarten A.D.H. Schalekamp, Willem A. Bax et al. · Circulation · 1995 · 763 citations

Medicine, Cardiology, Genetics +11