Concepedia

The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover

Miyuki Bohgaki, Anne Hakem, M J Halaby, Toshiyuki Bohgaki, Q Li, Pierre-Antoine Bissey, Jonathan Shloush, Thomas Kislinger, Oliva Sánchez, Yi Sheng,

Cell Death and Differentiation · 2013 · 47 citations · 35 references

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35

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese et al. · Nature · 2006 · 1.8K citations

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DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2

Atsushi Hirao, Young‐Yun Kong, Shuhei Matsuoka et al. · Science · 2000 · 1.3K citations

The BRCT Domain Is a Phospho-Protein Binding Domain

Xiaochun Yu, Claudia C.S. Chini, Miao He et al. · Science · 2003 · 872 citations

, , +11

Ataxia telangiectasia-mutated phosphorylates Chk2 <i>in vivo</i> and <i>in vitro</i>

Shuhei Matsuoka, Galit Rotman, Akira Ogawa et al. · Proceedings of the National Academy of Sciences · 2000 · 818 citations · Full text

Pirh2, a p53-Induced Ubiquitin-Protein Ligase, Promotes p53 Degradation

Roger Leng, Yunping Lin, Weili Ma et al. · Cell · 2003 · 714 citations · Full text

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