c-Rel Is a Target of Pentoxifylline-Mediated Inhibition of T Lymphocyte Activation

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

W. Michael Flanagan, Blaise Corthésy, Richard J. Bram et al. · Nature · 1991 · 1.1K citations

Transcriptional Regulation, Signal Transduction, Cell Regulation +12

Identification of a Putative Regulator of Early T Cell Activation Genes

Jeng‐Pyng Shaw, Paul J. Utz, David B. Durand et al. · Science · 1988 · 949 citations

Lymphocyte Development, T-regulatory Cell, Immunology +21

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

Frank Köntgen, Raelene J. Grumont, Andreas Strasser et al. · Genes & Development · 1995 · 726 citations · Full text

Lymphocyte Development, T-regulatory Cell, Immunology +19

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

Elizabeth Ann Emmel, Cornelis L. Verweij, David B. Durand et al. · Science · 1989 · 677 citations

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

James D. Fraser, Bryan Irving, Gerald R. Crabtree et al. · Science · 1991 · 644 citations

Signal Transduction Pathways, Adaptive Immune System, T-regulatory Cell +17