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Combinatorial mutagenesis of three major groove-contacting residues of EcoRI: single and double amino acid replacements retaining methyltransferase-sensitive activities

Combinatorial MutagenesisEngineeringBiotransformationBiochemistryNatural SciencesBiotechnologyMolecular BiologySynthetic BiologyMethyltransferase-sensitive ActivitiesEnzymatic ModificationProtein BiosynthesisMutagenesis