HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3 - Concepedia

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HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

DOI Full Paper Access

115

Citations

40

References

2011

Year

Federica Limana, Grazia Esposito, Daniela D’Arcangelo, Anna Di Carlo, Sveva Romani, G Melillo, Antonella Mangoni, Chiara Bertolami, Giulio Pompilio, Antonia Germani,

Abstract

HMGB1 injected into chronically failing hearts enhanced LV function and attenuated LV remodelling; these effects were associated with cardiac regeneration, increased collagenolytic activity, miR-206 overexpression and miR-206 -mediated inhibition of TIMP-3.

References

	Year	Citations

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