Identification of an interferon gamma homologue in Fugu, Takifugu rubripes

A general method applicable to the search for similarities in the amino acid sequence of two proteins

Saul B. Needleman, Christian D. Wunsch · Journal of Molecular Biology · 1970 · 11.5K citations

Life Sciences, Biochemistry, Bioinformatics +13

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

Henrik Nielsen, Jacob Engelbrecht, Søren Brunak et al. · Protein Engineering Design and Selection · 1997 · 5.4K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Prediction of complete gene structures in human genomic DNA

Chris Burge, Samuel Karlin · Journal of Molecular Biology · 1997 · 4.3K citations

Life Sciences, Bioinformatics, Genetics +16

Enhanced genome annotation using structural profiles in the program 3D-PSSM 1 1Edited by J. Thornton

Lawrence A. Kelley, Robert M. MacCallum, Michael J.E. Sternberg · Journal of Molecular Biology · 2000 · 1.5K citations

Life Sciences, Bioinformatics, Biology +15

Cloning and Expression of the Chicken Interferon-γ Gene

M. Digby, John W. Lowenthal · Journal of Interferon & Cytokine Research · 1995 · 246 citations

Life Sciences, Immunology, Molecular Biology +12