Nucleic Acids Research · 2005 · 976 citations · 7 references
Life SciencesBiochemistryBioinformaticsProtein BiochemistryProteomicsProteomics InformaticsMotif DiscoveryProtein Function AnnotationProtein IdentificationProtein MotifsProtein Sequence AnalysisDatabase SearchingMotif Database CurationProtein Family AnalysisProtein Reference Databases
The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to a documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE database is now complemented by a series of rules that can give more precise information about specific residues. During the last 2 years, the documentation and the ScanProsite web pages were redesigned to add more functionalities. The latest version of PROSITE (release 19.11 of September 27, 2005) contains 1329 patterns and 552 profile entries. Over the past 2 years more than 200 domains have been added, and now 52% of UniProtKB/Swiss-Prot entries (release 48.1 of September 27, 2005) have a cross-reference to a PROSITE entry. The database is accessible at http://www.expasy.org/prosite/.
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Recent improvements to the PROSITE database
Nicolas Hulo · Nucleic Acids Research · 2003 · 417 citations · Full text
Automated annotation of microbial proteomes in SWISS-PROT
Alexandre Gattiker, Karine Michoud, Catherine Rivoire et al. · Computational Biology and Chemistry · 2003 · 128 citations