Deletion of 12/15-Lipoxygenase Alters Macrophage and Islet Function in NOD-Alox15null Mice, Leading to Protection against Type 1 Diabetes Development - Concepedia

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Publication | Open Access

Deletion of 12/15-Lipoxygenase Alters Macrophage and Islet Function in NOD-Alox15null Mice, Leading to Protection against Type 1 Diabetes Development

DOI Full Paper Access

44

Citations

34

References

2013

Year

S. Green-Mitchell, Sarah A. Tersey, Banumathi K. Cole, Kaiwen Ma, Norine Kuhn, Tina D. Cunningham, Nelly A. Maybee, S. K. Chakrabarti, Marcia McDuffie, David Taylor,

Abstract

These results suggest that 12/15-LO affects islet and macrophage function, causing inflammation, and leading to autoimmunity and reduced beta cell mass.

References

	Year	Citations

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