Oscillating Crystallization of (+) and (–) Enantiomers during Resolution by Entrainment of 2‐Azabicyclo[2.2.1]hept‐5‐en‐3‐one

Abstract

Lamellar twinning of opposite enantiomers explains why the enantiomeric composition of a supersaturated solution oscillates during resolution by preferential crystallization of the bicyclic lactam (1; see diagram on the right).