Endothelial Nitric Oxide Synthase Inhibits G<sub>12/13</sub>and Rho-Kinase Activated by the Angiotensin II Type-1 Receptor - Concepedia

Concepedia

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Endothelial Nitric Oxide Synthase Inhibits G<sub>12/13</sub>and Rho-Kinase Activated by the Angiotensin II Type-1 Receptor

DOI Full Paper Access

39

Citations

45

References

2008

Year

Hiroyuki Suzuki, Keita Kimura, Heigoro Shirai, Kunie Eguchi, Sadaharu Higuchi, Akinari Hinoki, Kazuhiro Ishimaru, Eugen Brailoiu, Danny N. Dhanasekaran, Laura N. Stemmle,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

The eNOS/NO cascade specifically targets the Rho/Rho-kinase system via inhibition of G(12/13) to prevent vascular migration induced by AngII, representing a novel signal cross-talk in cardiovascular protection by NO.

References

	Year	Citations

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