Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

Peter C. Maisonpierre, Leonardo Belluscio, Stephen P. Squinto, +4

Science

Nt-3 Messenger RnaNeurotrophic Factor RelatedMolecular NeuroscienceNeurogenomicsDevelopmental Biology +10

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

Andreas Höhn, Joachim Leibrock, Karen A. Bailey, +1

Nature

NeuroregenerationNeuroanatomyNeurogenesisNeurologyNeuroscience +7

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

Craig Crowley, Susan D. Spencer, Merry Nishimura, +8

Cell

Developmental BiologyNeurophysiologyNeuroanatomyBrain DevelopmentPhysiology +11

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development

Kevin R. Jones, Isabel Fariñas, Carey Backus, +1

Cell

NeuroregenerationDevelopmental BiologyBrain DevelopmentNeuron DevelopmentNeurological Function +10

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene

Richard J. Smeyne, Rüdiger Klein, Andreas Schnapp, +5

Nature

Knockout MouseMolecular NeuroscienceMolecular PhysiologySignal TransductionSevere Sensory +10

The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

Rüdiger Klein, Venkata Nanduri, Shuqian Jing, +7

Cell

Brain-derived Neurotrophic FactorSignal TransductionSignaling PathwayReceptor Tyrosine KinaseNeuropeptide Receptor +6

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

Stephen P. Squinto, Trevor N. Stitt, Thomas H. Aldrich, +9

Cell

Brain-derived Neurotrophic FactorSynaptic PlasticitySignal TransductionNerve Growth FactorNeurotransmission +8

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

Dan Soppet, Enrique Escandón, Johnne Maragos, +9

Cell

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseNeuropeptide ReceptorNeuroscience +4

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

Patrik Ernfors, Kuo-Fen Lee, Jan Kučera, +1

Cell

Peripheral Nerve InjuryNeuroanatomyMedicineMotor SystemLimb Proprioceptive Afferents +9

The neurotrophic factor concept: a reexamination

Sigrun I. Korsching

Journal of Neuroscience