Improving Pharmaceutical Product Development and Manufacturing: Impact on Cost of Drug Development and Cost of Goods Sold of Pharmaceuticals

The price of innovation: new estimates of drug development costs

Joseph A. DiMasi, Ronald W. Hansen, Henry G. Grabowski · Journal of Health Economics · 2003 · 4.3K citations · Full text

Pharmacy, Pharmaceutical Policy, Pharmacoeconomics +14

Estimating The Cost Of New Drug Development: Is It Really $802 Million?

Christopher Adams, Van V. Brantner · Health Affairs · 2006 · 910 citations

Pharmacy, Pharmacoeconomics, Drug Approval Processes +10

Cost of innovation in the pharmaceutical industry

Joseph A. DiMasi, Ronald W. Hansen, Henry G. Grabowski et al. · Journal of Health Economics · 1991 · 763 citations · Full text

Pharmacy, Innovation Management, Pharmacoeconomics +12

Returns on Research and Development for 1990s New Drug Introductions

Henry G. Grabowski, John M. Vernon, Joseph A. DiMasi · PharmacoEconomics · 2002 · 313 citations

Medicine, Pharmacology, Drug Discovery +2

The development factory: Unlocking the potential of process innovation

John Bessant · Research Policy · 1997 · 289 citations

Management, Industrial Engineering, Innovation Management +14