Decreased level of kynurenic acid in cerebrospinal fluid of relapsing-onset multiple sclerosis patients

Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage

Peter Werner, David Pitt, Cedric S. Raine · Annals of Neurology · 2001 · 502 citations

Life Sciences, Neurology, Neuroscience +17

Autoimmune encephalomyelitis ameliorated by AMPA antagonists

Terence Smith, Anthony Groom, Bin Zhu et al. · Nature Medicine · 2000 · 466 citations

Life Sciences, Neurobiology, Neuroscience +14

Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

Melvyn P. Heyes, Cai Y. Chen, Eugene O. Major et al. · Biochemical Journal · 1997 · 217 citations · Full text

Life Sciences, Immunology, Pharmacology +14

Identification and quantification of kynurenic acid in human brain tissue

Waldemar A. Turski, Masayuki Nakamura, W. P. Todd et al. · Brain Research · 1988 · 216 citations

Life Sciences, Biochemistry, Neuroscience +8

A mechanism of quinolinic acid formation by brain in inflammatory neurological disease: Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate

Melvyn P. Heyes, Kuniaki Saito, Eugene O. Major et al. · Brain · 1993 · 171 citations

Life Sciences, Neurobiology, Neuroscience +16