Box-behnken design for the optimization of formulation variables of indomethacin coprecipitates with polymer mixtures

Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices

Tsunehiko Higuchi · Journal of Pharmaceutical Sciences · 1963 · 4.7K citations

Solid Matrices, Pharmaceutical Science, Sustained‐action Medication +9

Some New Three Level Designs for the Study of Quantitative Variables

George E. P. Box, D. W. Behnken · Technometrics · 1960 · 3.8K citations

Numerical Analysis, Quantitative Methods, Engineering +18

Pharmacokinetics of indomethacin

Gunnar Alván, Michael Orme, Leif Bertilsson et al. · Clinical Pharmacology & Therapeutics · 1975 · 240 citations

Preparation of Controlled-Release Microspheres of Ibuprofen with Acrylic Polymers by a Novel Quasi-Emulsion Solvent Diffusion Method.

Kawashima, Handa, Takéuchi et al. · 岐阜藥科大學紀要 = The annual proceedings of Gifu College of Pharmacy · 1990 · 150 citations

Engineering, Micro-encapsulation, Drug Delivery Systems +7

Physical Characterization and Dissolution Properties of lbuprofen:Eudragit Coprecipitates

M. Serpil Kislalioglu, Mansoor A. Khan, C.W. Blount et al. · Journal of Pharmaceutical Sciences · 1991 · 85 citations

Chemical Engineering, Engineering, Supercritical Fluid Chromatography +6