Concepedia

Modelling telomere shortening and the role of oxidative stress

Carole J. Proctor, Thomas B. L. Kirkwood

Mechanisms of Ageing and Development · 2002 · 97 citations · 25 references

DOI

Concepts

References

25

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

, , +11

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

Christopher M. Counter, Ariel A. Avilion, Catherine LeFeuvre et al. · The EMBO Journal · 1992 · 2.1K citations · Full text

, , +14

Telomere states and cell fates

Elizabeth H. Blackburn · Nature · 2000 · 1.4K citations

, , +14

Telomere end-replication problem and cell aging

Michael Z. Levy, Richard Allsopp, A. B. Futcher et al. · Journal of Molecular Biology · 1992 · 1.1K citations

, , +12

Long G Tails at Both Ends of Human Chromosomes Suggest a C Strand Degradation Mechanism for Telomere Shortening

Yoko Hirose, John P. Langmore · Cell · 1997 · 907 citations · Full text

, , +8