Discovery of novel indazole-linked triazoles as antifungal agents

New Azole Antifungals. 3. Synthesis and Antifungal Activity of 3-Substituted-4(3<i>H</i>)-quinazolinones

Javier Bartrolí, Enric Turmo, M. ALGUERO et al. · Journal of Medicinal Chemistry · 1998 · 213 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Yeast cytochrome P-450 catalyzing lanosterol 14 alpha-demethylation. II. Lanosterol metabolism by purified P-450(14)DM and by intact microsomes.

Yuri Aoyama, Yuichi Yoshida, Ryosuke Sato · Journal of Biological Chemistry · 1984 · 211 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

In Vitro Activity of a New Oral Triazole, BMS-207147 (ER-30346)

J Fung-Tomc, E Huczko, Beatrice Minassian et al. · Antimicrobial Agents and Chemotherapy · 1998 · 183 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +5

Cytochrome P-450-dependent oxidation of lanosterol in cholesterol biosynthesis. Microsomal electron transport and C-32 demethylation.

J M Trzaskos, W D Bowen, Ali Shafiee et al. · Journal of Biological Chemistry · 1984 · 95 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +16

Identification of 2-(4-Benzyloxyphenyl)-<i>N</i>- [1-(2-pyrrolidin-1-yl-ethyl)-1<i>H</i>-indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of Obesity

Andrew J. Souers, Ju Gao, Michael E. Brune et al. · Journal of Medicinal Chemistry · 2005 · 89 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17