Concepedia

Characterisation of Acute Murine Dextran Sodium Sulphate Colitis: Cytokine Profile and Dose Dependency

Bernhard Egger, Mona Bajaj‐Elliott, Thomas T. MacDonald, Roman Inglin, Viktor E. Eysselein, Markus W. Büchler

Digestion · 2000 · 377 citations · 34 references

DOI

Abstract

Minor variations in fluid consumption do not affect the severity of DSS-induced injury in mice. The acute murine DSS colitis model is useful for studying the pathophysiological aspects of colonic inflammatory diseases as IBD and for evaluating new potential therapeutic agents

References

34

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature · 1997 · 3.6K citations

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A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

Isao Okayasu, Shigeru Hatakeyama, Masahiro Yamada et al. · Gastroenterology · 1990 · 2.4K citations

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Clinicopathologic study of dextran sulfate sodium experimental acute colitis

Kazuko Shichijo, Mutsumi Matuu, Yuji Ikeda et al. · The Japanese Journal of Pharmacology · 1998 · 1.9K citations · Full text

Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines

Levinus A. Dieleman, Mary Palmen, Halil Akol et al. · Clinical & Experimental Immunology · 1998 · 1.2K citations · Full text

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Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice

Levinus A. Dieleman, Ben U. Ridwan, Gary S. Tennyson et al. · Gastroenterology · 1994 · 675 citations

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