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Reassessment of CXCR4 Chemokine Receptor Expression in Human Normal and Neoplastic Tissues Using the Novel Rabbit Monoclonal Antibody UMB-2

Thomas Fischer, Falko Nagel, Stefan Jacobs, Ralf Stumm, Stefan Schulz

PLoS ONE · 2008 · 66 citations · 31 references

DOIFull text

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Abstract

Thus, the rabbit monoclonal antibody UMB-2 may prove of great value in the assessment of the CXCR4 receptor status in a variety of human tumors during routine histopathological examination.

References

31

Involvement of chemokine receptors in breast cancer metastasis

Anja Müller, Bernhard Homey, Hortensia Soto et al. · Nature · 2001 · 5.3K citations

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CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

M. Endres, Paul R. Clapham, Mark Marsh et al. · Cell · 1996 · 662 citations · Full text

CXCR4 Regulates Interneuron Migration in the Developing Neocortex

Ralf Stumm, Chun Zhou, Toshiaki Ara et al. · Journal of Neuroscience · 2003 · 451 citations · Full text

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CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer

Tomohiko Mori, Ryuichiro Doi, Masayuki Koizumi et al. · Molecular Cancer Therapeutics · 2004 · 407 citations · Full text

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Silencing of <i>CXCR4</i> Blocks Breast Cancer Metastasis

Zhongxing Liang, Younghyoun Yoon, John R. Votaw et al. · Cancer Research · 2005 · 395 citations · Full text