Concepedia

Publication | Open Access

A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole

DOIFull Paper Access

72

Citations

43

References

2010

Year

Zaida García‐Casado, Ángel Guerrero‐Zotano, Antonio Llombart‐Cussac, Ana Calatrava, Antonio Fernández‐Serra, Amparo Ruiz-Simón, Joaquín Gavilá, Miguel Ángel Climent, Sergio Almenar, José Cervera-Deval,
BMC Cancer

Abstract

Our study reveals that the rs4646 polymorphism identifies a subgroup of stage II-III ER/PgR [+] BC patients with poor response to neoadjuvant letrozole and poor prognosis. Testing for the rs4646 polymorphism could be a useful tool in order to orientate the treatment in elderly BC patients.

References

YearCitations

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