Some developments in the phosphitetriester method for synthesis of oligonucleotides

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

Serge L. Beaucage, Marvin H. Caruthers · Tetrahedron Letters · 1981 · 2K citations

Pharmacy, Biochemistry, Molecular Biology +7

Synthesis of deoxyoligonucleotides on a polymer support

Mark D. Matteucci, M. H. CARUTHERS · Journal of the American Chemical Society · 1981 · 881 citations

Natural Sciences, Chemistry, Nucleic Acid Chemistry +6

An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides

Lincoln J. McBride, Marvin H. Caruthers · Tetrahedron Letters · 1983 · 513 citations

Life Sciences, Biochemistry, Molecular Biology +10

Synthesis of thymidine oligonucleotides by phosphite triester intermediates

Robert L. Letsinger, Willie B. Lunsford · Journal of the American Chemical Society · 1976 · 281 citations

Pharmacy, Chemistry, Molecular Biology +11

Nucleotide chemistry. XX. Phosphite coupling procedure for generating internucleotide links

Robert L. Letsinger, Jeffrey L. Finnan, George A. Heavner et al. · Journal of the American Chemical Society · 1975 · 149 citations

Pharmacy, Molecular Biology, Bioorthogonal Chemistry +7