Concepedia

Bronchoscopy-Derived Correlates of Lung Injury following Inhalational Injuries: A Prospective Observational Study

Samuel Jones, Haibo Zhou, Shiara Ortiz‐Pujols, Robert Maile, M Herbst, Benny L. Joyner, Hongtao Zhang, Matthew J. Kesic, Ilona Jaspers, Kathleen A. Short,

PLoS ONE · 2013 · 40 citations · 31 references

DOIFull text

Open access

Abstract

Independently of several factors including initial inhalational injury severity, infection, and extent of surface burns, high early levels of IL-10 and low levels of IL-12p70 in the central airways are associated with ALI in patients intubated after acute burn/inhalation injury. Lower airway secretions can be collected serially in critically ill burn/inhalation injury patients and may yield important clues to specific pathophysiologic pathways.

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Circulating mitochondrial DAMPs cause inflammatory responses to injury

Qin Zhang, Mustafa Raoof, Yu Chen et al. · Nature · 2010 · 3.6K citations · Full text

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Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

Jonathan Boomer, Kathleen To, Kathy Chang et al. · JAMA · 2011 · 1.7K citations · Full text

The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation

Intensive Care Medicine · 2011 · 590 citations · Full text

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Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

Tamás Dolinay, Young Sam Kim, Judie A. Howrylak et al. · American Journal of Respiratory and Critical Care Medicine · 2012 · 542 citations · Full text

Prognostic and Pathogenetic Value of Combining Clinical and Biochemical Indices in Patients With Acute Lung Injury

Lorraine B. Ware, Tatsuki Koyama, Dean Billheimer et al. · CHEST Journal · 2009 · 283 citations · Full text

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