Concepedia

Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

Ruth Pidsley, Joana Viana, Eilís Hannon, Helen Spiers, Claire Troakes, Safa Al‐Saraj, Naguib Mechawar, Gustavo Turecki, Leonard C. Schalkwyk, Nicholas J. Bray,

Genome biology · 2014 · 165 citations · 29 references

DOIFull text

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Abstract

Our data support the hypothesis that schizophrenia has an important early neurodevelopmental component, and suggest that epigenetic mechanisms may mediate these effects.

References

29

WGCNA: an R package for weighted correlation network analysis

Peter Langfelder, Steve Horvath · BMC Bioinformatics · 2008 · 27.8K citations · Full text

Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

Gordon K. Smyth · Statistical Applications in Genetics and Molecular Biology · 2004 · 11.9K citations

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Biological insights from 108 schizophrenia-associated genetic loci

Kai-How Farh, Brendan Bulik‐Sullivan · Nature · 2014 · 8K citations · Full text

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A General Framework for Weighted Gene Co-Expression Network Analysis

Bin Zhang, Steve Horvath · Statistical Applications in Genetics and Molecular Biology · 2005 · 5.9K citations

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Edward M. Scolnick · Nature · 2009 · 5K citations · Full text

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