Publication | Closed Access
Identification of Cystathionine β‐Synthase Inhibitors Using a Hydrogen Sulfide Selective Probe
158
Citations
20
References
2013
Year
Drug TargetSelective Fluorogenic ProbeChemical BiologyPharmaceutical ChemistryPre-clinical PharmacologyMolecular PharmacologyMedicinal ChemistryCystathionine β‐Synthase InhibitorsInhibitory ActivityOnline DeliveryBiochemistryMechanism Of ActionCystathionine β-Synthase ActivityDrug DevelopmentPharmacologyNatural SciencesRational Drug DesignMedicineDrug Discovery
Buzzing with activity: A hydrogen sulfide selective fluorogenic probe, 7-azido-4-methylcoumarin (AzMC), serves as a highly sensitive assay for cystathionine β-synthase activity, and is suitable for the high-throughput discovery of novel enzyme inhibitors. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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