Concepedia

Adenanthin targets proteins involved in the regulation of disulphide bonds

Angelika Muchowicz, Małgorzata Firczuk, Justyna Chlebowska, Dominika Nowis, Joanna Stachura, Joanna Barankiewicz, Anna Trzeciecka, Szymon Kłossowski, Ryszard Ostaszewski, Radosław Zagożdżon,

Biochemical Pharmacology · 2014 · 35 citations · 8 references

DOI

Concepts

References

8

Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62

James R. Matthews, Naomi Wakasugi, Jean‐Louis Virelizier et al. · Nucleic Acids Research · 1992 · 824 citations · Full text

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Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action.

Arne Holmgren · Journal of Biological Chemistry · 1979 · 327 citations · Full text

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Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells

Chuanxu Liu, Qianqian Yin, Huchen Zhou et al. · Nature Chemical Biology · 2012 · 223 citations

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The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resonance Imaging

Bénédicte F. Jordan, Matthew Runquist, Natarajan Raghunand et al. · Clinical Cancer Research · 2005 · 62 citations · Full text

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Studies toward Novel Peptidomimetic Inhibitors of Thioredoxin–Thioredoxin Reductase System

Szymon Kłossowski, Angelika Muchowicz, Małgorzata Firczuk et al. · Journal of Medicinal Chemistry · 2011 · 43 citations

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