Bénédicte F. Jordan

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

Pierre Sonveaux, Frédérique Végran, Thies Schroeder et al. · Journal of Clinical Investigation · 2008 · 1.6K citations · Full text

Chemoprevention Strategy, Metabolic Remodeling, Cancer Biology +18

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

Massimiliano Mazzone, Daniela Dettori, Rodrigo Leite de Oliveira et al. · Cell · 2009 · 802 citations · Full text

Oncology, Angiogenesis, Medicine +10

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

Julián Aragonés, Martin Schneider, Katie Van Geyte et al. · Nature Genetics · 2008 · 475 citations · Full text

Biochemistry, Redox Regulator, Physiology +9

Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population

Damya Laoui, Eva Van Overmeire, Giusy Di Conza et al. · Cancer Research · 2013 · 400 citations · Full text

Tumor-associated Macrophages, Immunology, Biological Microenvironments +17

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

Yukiji Takeda, Sandra Costa, Estelle Delamarre et al. · Nature · 2011 · 287 citations · Full text

Inflammation, Thrombosis, Vascular Disease +15