A double‐blind, placebo‐controlled oral challenge study with lyophilized larvae and antigen of the fish parasite, <i>Anisakis simplex</i>

Abstract

The ingestion of 100 lyophilized A. simplex larvae, or its equivalent in antigen, does not induce clinical symptoms in individuals with a clinical history and laboratory findings of hypersensitivity to A. simplex. The data suggest that only the ingestion of live larvae may be capable of inducing allergic manifestations.