The Chronic Kidney Disease Epidemiology Collaboration Equation Outperforms the Modification of Diet in Renal Disease Equation for Estimating Glomerular Filtration Rate in Chronic Systolic Heart Failure

Abstract

The CKD-EPI equation more accurately estimates measured GFR than the sMDRD equation in CHF patients, with less bias and greater accuracy and precision. The prognostic power of all GFR assessments was equivalent. Based on better performance and equal risk prediction, we believe the CKI-EPI equation should be the preferred creatinine-based GFR estimation method in heart failure patients, particularly those with preserved or moderately impaired renal function.