Concepedia

A rationally designed form of the TLR5 agonist, flagellin, supports superior immunogenicity of Influenza B globular head vaccines

Langzhou Song, Ge Liu, Scott Umlauf, Xiangyu Liu, Hong Li, Haijun Tian, Lucia Reiserová, Fuxiang Hou, Rodney Bell, Lynda Tussey

Vaccine · 2014 · 18 citations · 12 references

DOI

Concepts

References

12

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky et al. · Nature · 2001 · 3.6K citations

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Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

Kelly D. Smith, Erica Andersen‐Nissen, Fumitaka Hayashi et al. · Nature Immunology · 2003 · 813 citations

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Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy

Koji Yonekura, Saori Maki-Yonekura, Keiichi Namba · Nature · 2003 · 752 citations

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Safety and Immunogenicity of an Inactivated Subvirion Influenza A (H5N1) Vaccine

John J. Treanor, James D. Campbell, Kenneth M. Zangwill et al. · New England Journal of Medicine · 2006 · 704 citations · Full text

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Structural Basis of TLR5-Flagellin Recognition and Signaling

Sung‐il Yoon, Oleg V. Kurnasov, Venkatesh Natarajan et al. · Science · 2012 · 577 citations

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