Male breast cancer.I. Histologic typing and grading of 187 Danish cases

Abstract

In a series comprising 265 male patients with breast cancer, histologic typing and grading were carried out in 187 cases using the WHO Classification. Among the 187 patients, a total of 30 cases of special cancer types were found (22 carcinomas and 8 sarcomas). There were no carcinomas of lobular type. The sarcomas in our series had a relatively high frequency and a favorable prognosis. Histologic grading was carried out in 150 carcinomas. The 30 cases of special types and 7 cases with insufficient tumor tissue were excluded. The distribution of the 150 cases was: 29% with Grade I, 54% with Grade II, and 17% with Grade III. The histologic grading was correlated with prognosis, and a significant fall in the 5-year survival rate was found from Grade I to II and from Grade II to III.