No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARδ and PPARγ act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma - Concepedia

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No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARδ and PPARγ act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma

51

Citations

45

References

2005

Year

L McGreavey, Faye Turner, Gillian Smith, Katherine Boylan, D. Timothy Bishop, David Forman, C. Roland Wolf, Jennifer H. Barrett

Pharmacogenetics and Genomics

Abstract

Our study confirmed the reduction in risk of colorectal cancer with regular NSAID use (odds ratio (OR) = 0.73, 95% confidence interval (CI) (0.56, 0.95)) but showed that none of the polymorphic genes studied appeared to modify the protective effect of regular NSAID use.

References

	Year	Citations

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