NMDA Preconditioning Protects against Seizures and Hippocampal Neurotoxicity Induced by Quinolinic Acid in Mice

Abstract

These results suggest that in vivo preconditioning with subtoxic doses of NMDA protected mice against seizures and cellular hippocampal death elicited by QA, probably through mechanisms involving NMDA receptors operating with adenosine A1 receptors.