An essential component of the decapping enzyme required for normal rates of mRNA turnover

New metal chelate adsorbent selective for proteins and peptides containing neighbouring histidine residues

Erich Hochuli, Heinz Döbeli, Alfred Schacher · Journal of Chromatography A · 1987 · 1.1K citations

Biochemistry, Natural Sciences, Peptide Engineering +7

A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.

Carolyn J. Decker, Robert Parker · Genes & Development · 1993 · 658 citations · Full text

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript.

Denise Muhlrad, Carolyn J. Decker, Roy Parker · Genes & Development · 1994 · 511 citations · Full text

The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon.

Peter Leeds, Stuart W. Peltz, Allan Jacobson et al. · Genes & Development · 1991 · 495 citations · Full text

Premature translational termination triggers mRNA decapping

Denise Muhlrad, Roy Parker · Nature · 1994 · 403 citations

Transcriptional Regulation, Genetics, Rna Biology +3