Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

I. Vermes, C. Haanen, H M Steffens-Nakken et al. · Journal of Immunological Methods · 1995 · 5.3K citations · Full text

Apoptosis, Autophagy, Annexin V +9

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

Tumor Biology, Oncogenic Agent, Medicine +10

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

Mitophagy, Signal Transduction, Mitochondrial Function +8

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

Naoufal Zamzami, Philippe Marchetti, Maria Castedo et al. · The Journal of Experimental Medicine · 1995 · 1.6K citations · Full text

Apoptosis, Cell Death, Molecular Biology +17

Inhibition of Bax Channel-Forming Activity by Bcl-2

Bruno Antonsson, Franco Conti, AnnaMaria Ciavatta et al. · Science · 1997 · 1K citations

Proteinlipid Interaction, Apoptosis, Cell Death +19